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His current project in the Hilt Laboratory focuses on the design of novel moiety imprinted polymer (MoIPs) structures to produce hydrogels with increased affinity for target pharmaceutical compounds, resulting in enhanced loading. In previous work, entire drug molecules have been imprinted for, which has limited applicability due to the high cost of many pharmaceutical compounds. In contrast, this current work imprints for general moieties (carbohydrates, oligosaccharides, etc.) of pharmaceutical drugs in order to produce recognition sites within polymeric networks. In theory, this will lead to a very broad range of therapeutic drugs that could be loaded and released from a given gel. |
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