Christina M. Payne, P.E., Ph.D.

Assistant Professor

Research Areas: Biophysics, Biopolymers, Biotechnology, Computational science, Energy, Enzymes, Molecular modeling

University of Kentucky, College of Engineering
Chemical and Materials Engineering - CME
159 FPAT
Lexington, KY 40506-0046
Phone: 859-257-2902
Fax: 859-323-1929


Ph.D., Chemical Engineering, Vanderbilt University , 2007

B.S., Chemical Engineering, Tennessee Technological University, 2002

Professional Experience

2012 – present Assistant Professor, University of Kentucky

Nov. 2011 – Aug. 2012 : Staff Scientist, National Renewable Energy Laboratory

Jan. 2011 – Nov. 2011: Postdoctoral Research Associate, National Renewable Energy Laboratory

Jan. 2008 – Jan. 2011: Process Engineer, URS Energy and Construction

Aug. 2003 – Dec. 2007: Department of Energy Computational Science Graduate Fellow

May 2005 – Aug. 2005: DOE CSGF Intern, Sandia National Laboratories

Selected Publications

Equally contributing

  1. C.M. Payne, M.G. Resch, L. Chen, M.F. Crowley, M.E. Himmel, L.E. Taylor, M. Sandgren, J. Ståhlberg, I. Stals, Z. Tan, and G.T. Beckham, “Glycosylated Linkers in Multi-Modular Lignocellulose Degrading Enzymes Dynamically Bind to Cellulose,” Proc. Natl. Acad. Sci. U.S.A., 110, 14646-14651 (2013).
  2. M. Kern, J.E. McGeehan, S.D. Streeter, R.N.A. Martin, K. Besser, L. Elias, W. Eborral, G.P. Malyon, C.M. Payne, M.E. Himmel, K. Schnorr, G.T. Beckham, S.M. Cragg, N.C. Bruce, S.J. McQueen-Mason, “Structural Characterization of a Family 7 Cellobiohydrolase from a Marine Animal Reveals Potential Mechanisms of Cellulase Salt Tolerance,” Proc. Natl. Acad. Sci. U.S.A., 110, 10189-10194 (2013).
  3. R. Kushwaha, and A.B. Downie, and C.M. Payne*, “Uses of Phage Display in Agriculture: Sequence Analysis and Comparative Modeling of Late Embryogenesis Abundant Client Proteins Suggests Protein-Nucleic Acid Binding Functionality,” Comput. Math. Methods Med., 2013, 470390 (2013).
  4. M.H. Momeni, C.M. Payne, H. Hansson, N.E. Mikkelsen, J. Svedberg, J., Å, Engström, Å., M. Sandgren, G.T. Beckham, and J. Ståhlberg, “Structural, Biochemical, and Computational Characterization of the Glycoside Hydrolase Family 7 Cellobiohydrolase of the Tree-killing Fungus Heterobasion irregulare,” J. Biol. Chem., 288, 5861-5872 (2013).
  5. D.W. Sammond, C.M. Payne, R. Brunecky, M.E. Himmel, M.F. Crowley, and G.T. Beckham, “Cellulase Linkers are Optimized Based on Domain Type and Function: Insights from Sequence Analysis, Biophysical Measurements, and Molecular Simulation,” PLoS ONE, 7, e48615 (2012).
  6. C.M. Payne, J. Baban, S.J. Horn, P.H. Backe A.S. Arvai, B. Dalhus, M. Bjørås, V.G.H. Eijsink, M. Sørlie, G.T. Beckham, and G. Vaaje-Kolstad, “Hallmarks of processivity in glycoside hydrolases from crystallographic and computational studies of the Serratia marcescens chitinases,” J. Biol. Chem., 287, 36322-36330 (2012).
  7. G.T. Beckham, Z. Dai, J.F. Matthews, M. Momany, C.M. Payne, W.S. Adney, S.E. Baker, and M.E. Himmel, “Harnessing Glycosylation to Improve Cellulase Activity,” Curr. Opin. Biotechnol., 23, 338-345 (2012).
  8. C.M. Payne, Y.J. Bomble, C.B. Taylor, C. McCabe, M.E. Himmel, M.F. Crowley, and G.T. Beckham, “Multiple Functions of Aromatic-Carbohydrate Interactions in a Processive Enzyme Tunnel Examined with Molecular Simulation,” J. Biol. Chem., 286, 41028-41035 (2011).
  9. C.M. Payne*, M.E. Himmel, M.F. Crowley, and G.T. Beckham, “Decrystallization of Oligosaccharides from the Cellulose 1b Surface with Molecular Simulation,” J. Phys. Chem. Lett., 2, 1546-1550 (2011).
  10. C.M. Payne*, X. Zhao, L. Vlcek, and P.T. Cummings, “Molecular Dynamics Simulation of ss-DNA Translocation Between Copper Nanoelectrodes Incorporating Electrode Charge Dynamics,” J. Phys. Chem. B, 112, 1712-1717 (2008).