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Home » Modulation of Leukocyte Mechanotransduction of Fluid Shear Stress by the Cell Membrane

Modulation of Leukocyte Mechanotransduction of Fluid Shear Stress by the Cell Membrane

Research Areas: Cellular/Molecular Biology, Inflammation, Leukocyte, Mechanotrasduction, Membrane, Shear Stress Cardiovascular/Respiratory

Departments: Biomedical Engineering

Primary Investigator: Hainsworth Shin

Fluid shear stresses due to blood flow controls leukocyte activity by down-regulating pseudopod formation and surface expression of CD18 adhesion molecules, key events during acute inflammation. These shear responses
prevent adhesion and microvascular e

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