The research laboratories housed in the Department of Biomedical Engineering and the investigators directing the labs are listed below. Click on the lab name to learn more.
Biomedical Instrumentation Laboratory (staff)
This laboratory provides an environment for teaching applied biomedical electronics, instrumentation and experimentation. It is also used by students who conduct independent studies in biomedical instrumentation.
Bio-Photonics Laboratory (Dr. Yu)
This laboratory develops optical spectroscopy/tomography for in-vivo measurements of blood flow, oxygenation and oxygen metabolism in normal and diseased tissues of animals and humans. The motivation is to explore the feasibility of optical instruments for diagnosis of various diseases and longitudinal monitoring of therapies. The goal is to create a strong bio-photonics research and teaching program, which vertically integrates physics, optics, engineering and clinical applications.
Cardiac Rhythm Laboratory (Dr. Patwardhan)
The focus of research conducted in the rhythm dynamics laboratory is on the use of linear and non-linear systems and signal analysis techniques to investigate the dynamics of cardiovascular function.
Cardiovascular Laboratory (Dr. Knapp / J. Evans)
Research conducted in this laboratory investigates changes in cardiovascular control in humans exposed to simulated space flight and countermeasures to cardiovascular deconditioning. The fluid mechanics of blood flow is also investigated.
Cellular Mechanobiology and Engineering Lab (Dr. Shin)
Our research addresses fundamental, but elusive, issues regarding the role of mechanical forces in controlling human biology, specifically identifying the cellular component(s) responsible for sensing and converting mechanical forces into a biological event (i.e., mechanotransduction). Current efforts focus on the involvement of fluid mechanics in regulating the functions of cardiovascular cells (e.g., endothelium, white blood cells) involved in physiological processes (e.g., inflammation, blood vessel remodeling). Our objective is to answer two basic questions: 1) how mechanical stresses serve as regulators of vascular cell activity and 2) how dysregulated vascular mechanotransduction contributes to the onset/progression of human diseases. For this purpose, we adopt a bioengineering approach at the interface between modern physics and the biological sciences to define the role of mechanics in the biology of the cell and, from these efforts, develop novel research tools, therapeutic approaches, and tissue engineering strategies.
Human Musculoskeletal Biomechanics Lab (Dr. Bazrgari)
Our research program focuses on the mechanical behaviors of the active neuromuscular and the passive musculoskeletal systems in the human body, and aims at controlling and managing musculoskeletal disorder.
Neural Systems Laboratory (Dr. Sunderam)
Our research focuses on the diagnosis of brain states using physiological measurements, modeling and signal analysis, for applications in epilepsy therapy, sleep monitoring, neuroprosthetics, and cognitive science. For more information, please see our lab page.
Bone Quality Laboratory (Dr. Pienkowski)
Mechanical testing of hard and soft tissues are the primary focus of this laboratory, two Instron servo-hydraulic mechanical testing systems provide compression, tension, bending and torsional testing capabilities of hard and soft tissue and a variety of prosthetic devices.
Regenerative Biomaterials Laboratory (Dr. Puleo)
The overall objective of the work conducted in this laboratory is to develop biomaterials that enable control of cellular events at the tissue-implant interface.